Cantho City is located in the center of the Mekong Delta. It is contiguous to 5 provinces: An Giang on the north, Dong Thap on the north-east, Hau Giang on the south, Kien Giang on the west, and Vinh Long on the east. Cantho has a complex of rivers and canals such as Hau, and Can Tho rivers, Thot Not, O Mon canals. Among them, the Hau Riveris considered a benefactor of this region, since yearly floods deposit large quantities of alluvia to the rice fields. Thank to that Cantho becomes "the green lungs of the Mekong Delta".The climate is harmonized with few of storms. It is hot, humid all year. Rainy season lasts from May to November, and dry season lasts from December to April. The annual average temperature is 27ºC.

Cantho is over its 200 years as the main town, once known as Tay Do and now one city of Vietnam. All of economic, culture activities closely relate to river and canals which like the 'street'. Cantho has simple, poetic beauty with well-off villages under shade of coconut trees.It is wonderful to take a boat trip along the riverbanks on fine weather days. On the east bank of Hau River is Ninh Kieu Wharf, which is well known for its beautiful location. Other interesting places are Bang Lang Stock Sanctuary, Cantho and My Khanh Tourist gardens and Cantho Market.